Novel Elongator Protein 2 Inhibitors Mitigating Tumor Necrosis Factor-α Induced Osteogenic Differentiation Inhibition

Table 1

Affinity constants of candidate compounds with ELP2 protein.

No.	Protein	Compound	Avg (M^-1 s^-1)	Avg (s^-1)	Avg KD (M)
1#	Elp2	1#
2#	Elp2	2#
3#	Elp2	3#
4#	Elp2	4#
5#	Elp2	5#
6#	Elp2	6#
7#	Elp2	7#
8#	Elp2	8#
9#	Elp2	9#
10#	Elp2	10#
11#	Elp2	11#
Blank	Elp2	DMSO