Review Article

Percutaneous versus Surgical Intervention for Severe Aortic Valve Stenosis: A Systematic Review

Figure 5

Recommendations from the 2020 guidelines of the American College of Cardiology and the American Heart Association for the treatment of patients with valvular heart disease. Clinical factors and imaging findings are shown in green and yellow boxes as well as AVR recommendations according to class (strength) of recommendation and level (quality) of evidence. Treatment recommendations are shown in red boxes. 1A, 1B-NR, 2aB-NR, 2a B-R, and 2b NR are the class of recommendation (COR) that indicates the strength of recommendation, including the estimated magnitude and assurance of advantage in relation to risk. The level of evidence (LOE) rates the quality of scientific evidence supporting the intervention on the basis of the type, quantity, and consistency of data from clinical trials and other sources. Ref. [7, 19, 20, 118150]. Abbreviations: AV = aortic valve stenosis; AVR-S = surgical aortic valve replacement; HF = heart failure; LVEF = left ventricular function; TAVR = transcatheter aortic valve replacement.