Review Article

Effect of Pericytes on Cerebral Microvasculature at Different Time Points of Stroke

Table 1

Methodological quality for each study included.

StudyABCDEFGHIJTotal

Makihara N et al. 2015 [15]++---++-+-5
Liu KF et al. 2001 [16]+----++-+-4
Renner O et al. 2003 [17]+----++-+-4
Duz B et al. 2007 [18]++---++---4
Sakuma R et al. 2016 [19]+----++---3
Shibahara T et al. 2020 [20]+----++-+-4
Zhang Y et al. 2020 [21]++---++-++6
Arimura K et al. 2012 [22]++---++-++6
Garbuzova-Davis S 2014 [23]+++--++-+-6
Zhai ZY et al. 2019 [24]+++--++-+-6
Garbuzova-Davis S et al. 2013 [25]++---++-+-5
Shin YJ et al. 2013 [26]++----+-+-4
Deguchi K et al. 2014 [27]++---++-+-5
Noh JS et al. 2015 [28]++----+-++5
Han D et al. 2015 [29]+++---+---4
Zhou YF et al. 2018 [30]++---++-++6
Wang F et al. 2020 [31]+++---+-+-5
Nishimura A et al. 2016 [32]+++--++-++7
Yemisci M et al. 2009 [7]++---++---4
Nakata M et al. 2017 [33]++---++-++6
Tan QS et al. 2017 [34]+-+--++---4
Jean LeBlanc N et al. 2018 [35]++---++-+-5

Studies meeting the 10 criteria of risk of bias: A: peer-reviewed publications; B: temperature control; C: random assignment of treatments or controls; D: model-blind induction; E: blinded assessment of outcomes; F: use of anesthetics without significant intrinsic cardioprotective effects; G: appropriate animal models (elderly, diabetic, or hypertensive); H: sample size calculation; I: compliance with animal welfare regulations; J: potential conflict-of-interest statements.