Predictive Value of Gray-Matter–White-Matter Ratio on Brain Computed Tomography for Delayed Encephalopathy after Acute Carbon Monoxide Poisoning: A Retrospective Cohort Study

Table 2

Logistic regression analysis for DEACMP.

		Std. error	Wald	value	Exp	95% CI
Univariate analysis
Age	0.019	0.017	1.274	0.259	1.019	0.986–1.053
Gender	0.263	0.512	0.265	0.607	1.301	0.477–3.550
Heart rate	0.032	0.018	3.322	0.068	1.033	0.998–1.069
Respiration rate	0.006	0.012	0.252	0.615	1.006	0.983–1.030
Mean arterial pressure	0.000	0.008	0.001	0.971	1.000	0.984–1.017
Exposure time	0.207	0.059	12.108	0.001	1.230	1.094–1.382
Time from end of exposure to admission	0.072	0.166	0.186	0.667	1.074	0.776–1.488
Time from end of exposure to brain CT	-0.008	0.042	0.039	0.843	0.992	0.914–1.076
Hyperbaric oxygen therapy	0.593	0.786	0.596	0.440	1.089	0.402–8.148
Number of hyperbaric oxygen therapy sessions	0.074	0.030	6.105	0.013	1.077	1.015–1.142
Alanine aminotransferase	0.043	0.015	7.696	0.006	1.044	1.013–1.076
Creatinine	0.012	0.010	1.430	0.232	1.012	0.993–1.031
pH	-1.305	4.753	0.075	0.784	0.271	0.000–3016.406
PO2	0.001	0.005	0.056	0.813	1.001	0.991–1.012
Base excess	-0.145	0.062	5.381	0.020	0.865	0.766–0.978
COHB (%)	-0.022	0.030	0.523	0.470	0.978	0.922–1.038
GWR-basal ganglia	-43.274	8.695	24.771	<0.001	0.000	0.000–0.000
GWR-cortices	-10.989	4.103	7.174	0.007	0.000	0.000–0.052
GWR-average	-21.130	6.327	0.001	<0.001	0.000	0.000–0.000
Multivariate analysis (model 1)
Exposure time	0.286	0.084	11.653	0.001	1.330	1.129–1.567
Number of hyperbaric oxygen therapy sessions	0.077	0.048	2.508	0.113	1.080	0.982–1.187
Alanine aminotransferase	0.053	0.022	5.615	0.018	1.054	1.009–1.102
GWR-basal ganglia	-50.272	10.602	22.484	<0.001	0.000	0.000–0.000
Multivariate analysis (model 2)
Exposure time	0.218	0.068	10.275	0.001	1.243	1.088–1.420
Number of hyperbaric oxygen therapy sessions	0.089	0.036	5.928	0.015	1.093	1.017–1.174
Alanine aminotransferase	0.044	0.018	5.747	0.017	1.045	1.008–1.084
GWR-cortices	-10.967	4.109	7.122	0.008	0.000	0.000–0.054
Multivariate analysis (model 3)
Exposure time	0.232	0.074	9.841	0.002	1.261	1.091–1.457
Number of hyperbaric oxygen therapy sessions	0.094	0.040	5.391	0.020	1.098	1.015–1.189
Alanine aminotransferase	0.052	0.020	6.553	0.010	1.053	1.012–1.096
GWR-average	-24.212	7.351	10.847	0.001	0.000	0.000–0.000

CI: confidence interval; DEACMP: delayed encephalopathy after acute carbon monoxide poisoning; GWR: gray-matter–white-matter ratio; COHB: carboxyhemoglobin.