Spleen Stiffness Performance in the Noninvasive Assessment of Gastroesophageal Varices after Transjugular Intrahepatic Portosystemic Shunts

Table 3

Diagnostic performance of SS, LS, SS/LS, LSPS, PH risk score, PSR, and varices risk score for evaluating the severity of GEVs in the post-TIPS long-term follow-up.

Characteristic	AUC (%)	Cutoff value	Sensitivity (%)	Specificity (%)	Youden index
Mild GEVs
SS	77.8	28.9	68.2	88.9	0.6
LS	70.9	7.9	91.0	50.0	0.4
SS/LS	56.9	3.5	76.2	55.6	0.3
LSPS	72.0	1.7	76.2	66.7	0.4
PH risk score	75.1	-0.1	95.2	55.6	0.5
PSR	65.7	6.0	77.3	66.7	0.4
Varices risk score	73.0	-0.7	76.2	66.7	0.4
Moderate GEVs
SS	82.0	29.9	83.3	78.9	0.6
LS	62.9	12.8	50.0	75.0	0.3
SS/LS	57.7	3.2	72.7	63.2	0.4
LSPS	68.4	3.1	63.6	78.9	0.4
PH risk score	68.9	5.0	63.6	78.9	0.4
PSR	64.0	4.6	83.3	52.6	0.4
Varices risk score	69.4	2.1	63.6	84.2	0.5
Severe GEVs
SS	82.4	37.7	71.4	95.8	0.7
LS	55.4	13.2	42.9	76.0	0.2
SS/LS	62.1	3.2	85.7	60.9	0.5
LSPS	84.5	3.3	85.7	82.6	0.7
PH risk score	83.2	6.8	85.7	87.0	0.7
PSR	82.7	2.6	71.4	91.7	0.6
Varices risk score	90.7	2.1	100.0	87.0	0.9

SS: spleen stiffness; LS: liver stiffness; SS/LS: spleen stiffness-to-liver stiffness ratio; LSPS: liver stiffness spleen-diameter-to-platelet-ratio score; PH risk score: portal hypertension risk score; PSR: platelet count-to-spleen diameter ratio; GEVs: gastroesophageal varices; TIPS: transjugular intrahepatic portosystemic shunt; AUC: areas under the receiver operating characteristic curve. AUC of SS was statistically compared with AUC of LS, SS/LS, LSPS, PH risk score, PSR, and varices risk score, respectively, in the same GEVs stage ().