Research Article

IL-6 Promotes the Proliferation and Immunosuppressive Function of Myeloid-Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer

Figure 3

IL-6 promoted MDSC proliferation in MIBC tissues. (a, b) Correlation between IL-6 (AOD and MFI) and MDSCs in MIBC tissues. (c) Experimental design of MDSC extraction and IL-6 treatment. (d) CCK-8 assays were used to test MDSCs with or without IL-6 treatment. (e) MDSC proliferation rates were evaluated according to fluorescence attenuation. (f, g) Flow cytometry images and statistical analysis of MDSCs from humans and mice with or without IL-6 treatment. , , and . AOD: average optical density; MFI: median fluorescence intensity.
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