The Relationship of Large-Artery Atherothrombotic Stroke with Plasma Trimethylamine N-Oxide Level and Blood Lipid-Related Indices: A Cross-Sectional Comparative Study

Table 1

General characteristics.

Characteristics	Stroke patients ()	Healthy controls ()	^1
Male sex, % ()	70.00 (35)	28.00 (14)	<0.01
Age, years,			0.01
Overweight or obesity, % ()	32.00 (16)	20.00 (10)	0.43
Smoking, % ()	38.00 (19)	4.00 (2)	<0.01
Alcohol, % ()	32.00 (16)	10.00 (5)	<0.01
Diabetes, % ()	42.00 (21)	8.00 (4)	<0.01
Hypertension, % (n)	72.00 (36)	26.00 (13)	<0.01
Volume of acute cerebral infarction, mm^3,			<0.01
Area of carotid artery plaque, mm^2,			0.95
TMAO, ng/mL,			<0.01
Lp-a, g/L,			<0.01
Apo-A1, g/L,			<0.01
Apo-B, g/L,			<0.01
Apo-A1/B ratio,			<0.01
TC, mmol/L,			0.12
HDL-C, mmol/L,			<0.01
LDL-C, mmol/L,			0.07
TG, mmol/L,			0.16
D-Dimer, IU/L,			<0.01
TT, s,			0.37

Abbreviations: SD: standard deviation; TMAO: trimethylamine N-oxide; Lp-a: lipoprotein-a; Apo-A1: apolipoprotein A1; Apo-B: apolipoprotein B; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; TT: thrombin time. ¹ value was obtained using chi-square tests or Fisher’s exact tests for categorical variables and Mann-Whitney tests for continuous variables.