Research Article

Pathological Change and Whole Transcriptome Alternation Caused by ePTFE Implantation in Myocardium

Table 2

The representative DEmRNAs in the top GO terms.

GO termCategoryRegulation stationRepresentative DEmRNAs

Inflammatory responseBiological processUpCCL2, CD180, CD44, CHI3L1, CXCL8, IL1RAP, IL34, TLR2
Extracellular spaceCellular componentUpADAMTS15, COL11A1, DKKL1, MMP14, NAPSA, NPC2, OAS3, TIMP1
Antigen bindingMolecular functionUpCD48, LAG3, TGFB1
Mitochondrial respiratory chain complex I assemblyBiological processDownACAD9, NDUFA11, NDUFB1, NDUFAF7, NDUFC1, NDUFS4, NDUFS5, OXA1L
MitochondrionCellular componentDownATP5H, COQ7, CPS1, DLAT, OXCT1, TIMM44, TRAK2, VDAC2
NADH dehydrogenase (ubiquinone) activityMolecular functionDownNDUFA12, NDUFA5, NDUFA7, NDUFB8, NDUFC1, NDUFC2, NDUFS1, NDUFS3