Bortezomib Inhibits Hypoxia-Induced Proliferation by Suppressing Caveolin-1/SOCE/[Ca<sup>2+</sup>]<sub>i</sub> Signaling Axis in Human PASMCs

<div>Effects of BTZ on the protein degradation of Caveolin-1 protein in human PASMCs under normoxia and hypoxia. Western blot (a) and line chart (b) representing the protein expression level of Caveolin-1 and p21 upon treatment with/without BTZ in the presence of CHX within a 24-hour time window in human PASMCs under normoxic and hypoxic conditions. 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BioMed Research International

fig4

Figure 4

Figure 4: Bortezomib Inhibits Hypoxia-Induced Proliferation by Suppressing Caveolin-1/SOCE/[Ca<sup>2+</sup>]<sub>i</sub> Signaling Axis in Human PASMCs 

BioMed Research International

Bortezomib Inhibits Hypoxia-Induced Proliferation by Suppressing Caveolin-1/SOCE/[Ca2+]i Signaling Axis in Human PASMCs

Figure 4

Bortezomib Inhibits Hypoxia-Induced Proliferation by Suppressing Caveolin-1/SOCE/[Ca²⁺]_i Signaling Axis in Human PASMCs