Research Article

Irisin Has a Protective Role against Osteoporosis in Ovariectomized Rats

Table 1

BMI, serum glucose, serum insulin, HOMA-IR, dry weight, ash weight, and calcium and phosphorus content in bone ash in all studies groups.

Group I (negative control)Group II (sham operated)Group III (OVX-nontreated)Group IV (OVX-irisin treated)

BMI (g/cm2)
, P = 0.62b, P <0.01c
Glucose (mg/dL)
, ,
Insulin (μIU/mL)
, ,
HOMA-IR
, ,
Dry wt. (mg/femur)
, ,
Ash wt. (mg/femur)
, ,
Bone Ca (mg/g ash)
, ,
Bone P (mg/g ash)
, ,

Significance level at . a value of significance versus negative control group, b value of significance versus sham-operated group, and c value of significance versus ovariectomized-nontreated group.