Interaction of Adiponectin Genotypes and Insulin Resistance on the Occurrence of Taiwanese Metabolic Syndrome
Table 4
Interactions of apM1 +45 genotypes, TNF-α -308 genotypes with TyG index, and TG/HDL-C ratio on the development of Taiwanese metabolic syndrome.
Variables
apM1 +45 genotypes
TNF-α -308 genotypes
TT
GG/GT
AA/AG
GG
With/without MetS# (OR (95% CI))†
With/without MetS# (OR (95% CI))†
With/without MetS# (OR (95% CI))†
With/without MetS# (OR (95% CI))†
TyG index
≥ 9.0
56/25
22.78 (9.56-54.30)
46/24
19.20 (7.96-46.31)
21/8
16.22 (4.65-56.59)
81/41
12.15 (4.38-33.75)
< 9.0
11/75
1.53 (0.58-4.01)
8/84
1.00 (ref.)
5/32
0.70 (0.23-2.11)
14/127
1.00 (ref.)
Test for interaction
(1 df);
(1 df);
TG/HDL-C ratio
≥ 4.2
57/20
21.56 (9.51-48.90)
43/24
13.30 (5.85-30.20)
20/5
24.83 (6.59-93.57)
80/39
12.88 (4.85-34.23)
< 4.2
10/80
0.91 (0.96-2.26)
11/84
1.00 (ref.)
6/35
0.74 (0.19-1.97)
15/129
1.00 (ref.)
Test for interaction
(1 df);
(1 df);
#Indicated the numbers of subjects with and without MetS, respectively. †Adjusted the effects of age and gender. OR: odds ratio; CI: confidence interval; TyG: triglyceride glucose; ref: reference. The value is < 0.01.