Senescence Osteoblast-Derived Exosome-Mediated miR-139-5p Regulates Endothelial Cell Functions

Figure 4

Effects of miR-139-5p on the senescence and apoptosis of vascular endothelial cells. (a) Expression of miR-139-5p after transfection with miR-139-5p mimic and inhibitor in endothelial cells (). (b) Senescent staining, Hoechst apoptosis staining, and TUNEL apoptosis staining of vascular endothelial cells after miR-139-5p mimic treatment and quantitative analysis (). (c) Senescent staining, Hoechst apoptosis staining, and TUNEL apoptosis staining of senescent vascular endothelial cells induced by D-gal after miR-139-5p inhibitor treatment and quantitative analysis ().

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