Increase in Free Hepatic Venous Pressure Response to Beta-Blockers Predicts Variceal Bleeding in Cirrhotic Patients

Table 2

Patients’ demographics, liver disease characteristics, and clinical presentation ().

	FHVP^7 decreased or unchanged ()	FHVP increased ()	value	Responders ()	Nonresponders ()	value
Mean age (years)			0.369			0.535
Gender male/female	19/21	15/7	0.182	27/19	7/9	0.386
Etiology virus/alcoholic/PBC^1/others	21/5/3/11	16/2/2/2	0.326	30/5/3/8	7/2/2/5	0.465
PLT^2 (×10^9/L)			0.410			0.446
TBil^3 (μmol/L)			0.089			0.531
Creatinine (μmol/L)			0.734			0.825
Albumin (g/L)			0.094			0.450
PT^4 (s)			0.603			0.018
INR^5			0.661			0.021
CTP^6 scores	7 (5-9)	6.5 (5-8)	0.799	7 (5-9)	6 (5-8)	0.117
CTP stage A/B/C	20/20/0	11/11/0	1.000	20/26/0	11/5/0	0.146
Ascites^8
No/mild/moderate/massive	15/12/12/1	9/10/3/0	0.374	16/17/12/1	8/5/3/0	0.698
Splenectomy yes/no	1/39	2/20	0.285	3/43	0/16	0.562
Median follow-up time (m)	11.50	13.00	0.740	13.00	10.50	0.331

¹PBC: primary biliary cirrhosis; ²PLT: platelets; ³TBil: total bilirubin; ⁴PT: prothrombin time; ⁵INR: international standard ratio; ⁶CTP: Child-Turcotte-Pugh; ⁷FHVP: free hepatic vein pressure; ⁸ascites: (1) mild: patients generally have abdominal distension, the ascites can only be detectable by an ultrasound examination, and the depth is <3 cm. (2) Moderate: the patient often has moderate and symmetrical abdominal distension, and the depth is 3–10 cm. (3) Massive: the patient has a significant bloating. The ascites detected by ultrasound occupy the entire abdominal cavity, and the depth is >10 cm.