Research Article
NaHS Alleviated Cell Apoptosis and Mitochondrial Dysfunction in Remote Lung Tissue after Renal Ischemia and Reperfusion via Nrf2 Activation-Mediated NLRP3 Pathway Inhibition
Figure 3
The effect of MCC950 on mitochondrial morphology, matrix metalloproteinase (MMP), respiratory control rate (RCR), adenosine-triphosphate (ATP), reactive oxygen species (ROS), apoptosis, and lung injury after renal ischemia reperfusion (RIR). The mitochondrial morphology was observed by TEM ((a), ). Bar graphs show the red/green fluorescence intensity (b), RCR (c), ATP (d), and ROS (e). The fluorescence image (f) and percentage of TUNEL-positive apoptotic cells (g) were measured by TUNEL assay. Lung injury was observed by H&E (h, ×400), and the H&E staining scores in the lung tissue were counted (i). Values are presented as the . vs. Con; # vs. RIR; except (a).
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