WGCNA-Based Identification of Hub Genes and Key Pathways Involved in Nonalcoholic Fatty Liver Disease

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Names</td><td class="align_center">Total</td><td class="align_center">Genes</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Hub genes in PPI network and hub genes in WGCNA</td><td class="align_center">15</td><td class="align_center">COPS5 RPS17 NDUFB8 UBL5 PSMA3 PSMA1 SF3B5 MRPL27 RPL26 PDCD5 NDUFA9 PFDN6 UQCRQ SNRPD2 PSMB3</td></tr><tr><td class="align_left">Hub genes in WGCNA</td><td class="align_center">29</td><td class="align_center">UCHL3 COMMD6 COA5 TAF11 MED18 BABAM1 GGCT DPY30 UQCC2 GEMIN7 ATP5MG BAG1 CNPY2 VAMP8 TIMM8B TBC1D7 DYNLT1 PARL ZBTB8OS ITIH4 NDUFAF5 SQOR ZNF563 TMEM141 RPAIN MYL6 MRPS21 CFDP1 SMIM7</td></tr><tr><td class="align_left">Hub genes in PPI network</td><td class="align_center">15</td><td class="align_center">PBK HSPE1 MRPL20 TSFM EMG1 ANAPC7 CHEK1 FBXW8 RFC4 SNRPA1 EZH2 CDC45 POLR1C PFDN4 ATP5L</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>15 shared hub genes in WGCNA and in PPI network via Venn diagram.</div>

BioMed Research International

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Table 2

Table 2: WGCNA-Based Identification of Hub Genes and Key Pathways Involved in Nonalcoholic Fatty Liver Disease 