Research Article
Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling
Figure 10
Cilengitide treatment inhibits the expression of VEGF and its downstream Ras/ERK/AKT signaling pathway of HUVECs. (a) Representative image of western blots for the protein expression of VEGF, Ras, p-ERK/EKR, and p-AKT/AKT under treatment with 0 μM, 1 μM, and 10 μM cilengitide. (b–e) Quantification of the protein expression levels. for each group. vs. 0 μM; vs. 0 μM.
(a) |
(b) |
(c) |
(d) |
(e) |