Research Article

Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling

Figure 10

Cilengitide treatment inhibits the expression of VEGF and its downstream Ras/ERK/AKT signaling pathway of HUVECs. (a) Representative image of western blots for the protein expression of VEGF, Ras, p-ERK/EKR, and p-AKT/AKT under treatment with 0 μM, 1 μM, and 10 μM cilengitide. (b–e) Quantification of the protein expression levels. for each group. vs. 0 μM; vs. 0 μM.
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