BioMed Research International

Research Article

Risk Factors and a Nomogram Model Establishment for Postoperative Delirium in Elderly Patients Undergoing Arthroplasty Surgery: A Single-Center Retrospective Study

Table 2

Risk factors of patients with POD by univariate and multivariable based on logistic regression analysis.


Characteristic	Univariate analyses		Multivariate analyses
Characteristic	OR (95% CI)	value	OR (95% CI)	value

Intraoperative blood loss	1.002 (0.997-1.007)	0.404	—	—
Operation duration	1.013 (0.999-1.026)	0.063^a	1.017 (1.000-1.035)	0.050
Glomerular filtration rate	1.274 (0.484-3.353)	0.623	—	—
C-reactive protein	0.655 (0.264-1.625)	0.361	—	—
Lactate dehydrogenase	2.450 (0.994-6.042)	0.052^a	4.364 (1.295-14.707)	0.017
Cholinesterase	4.107 (1.813-9.305)	0.001^a	4.640 (1.654-13.013)	0.004
Cystatin C	4.950 (2.525-10.882)	<0.001^a	5.283 (1.603-17.415)	0.006
Erythrocyte sedimentation rate	1.000 (0.472-2.117)	1.000	—	—
Hemoglobin	1.158 (0.547-2.453)	0.702	—	—
Arrhythmia	3.528 (1.612-7.720)	0.002^a	5.253 (1.870-14.756)	0.002
White blood cell count	1.435 (0.622-3.315)	0.397	—	—
Absolute neutrophil count	1.630 (0.781-3.404)	0.193^a	2.152 (0.804-5.761)	0.127
Lymphocyte count	0.000	0.999	—	—
Monocyte count	0.812 (0.391-1.687)	0.576	—	—
Eosinophil count	0.491 (0.043-5.572)	0.566	—	—
Basophil count	1.000	1.000	—	—
Total protein	1.231 (0.593-2.554)	0.577	—	—
Albumin	0.924 (0.423-2.017)	0.842	—	—
Total bilirubin	3.062 (1.014-9.248)	0.047^a	1.240 (0.199-7.711)	0.817
Direct bilirubin	1.829 (0.749-4.462)	0.185^a	1.150 (0.251-5.269)	0.858
Alanine transaminase	0.482 (0.085-2.742)	0.411	—	—
Aspartate aminotransferase	0.590 (0.181-1.923)	0.381	—	—
Alkaline phosphatase	0.000	0.999	—	—
Creatinine	2.115 (0.938-4.773)	0.071^a	0.705 (0.206-2.414)	0.578
Blood urea nitrogen	1.725 (0.741-4.014)	0.206	—	—
Calcium	1.573 (0.614-4.032)	0.346	—	—
Magnesium		0.120^a		0.559
Lower	1		1
Normal	1 (0.073-13.644)		3.070 (0.139-67.724)
Raised	0.284 (0.029-2.824)		1.347 (0.088-20.677)

^aRepresents the significant value of univariate analysis (); significant values of multivariate analyses are in bold (). POD: postoperative delirium.