The Natural History and Reperfusion Therapy Outcomes of Acute Ischemic Stroke due to Isolated M2 Occlusions

Table 1

Baseline patient characteristics.

Characteristics	NRT ()	IVT ()	EVT ()	//	value
Age, , years				12.42^a	<0.01
Male (%)	13 (52)	12 (44.44)	11 (61.11)	1.21^b	0.547
Left hemisphere (%)	17 (68)	15 (55.56)	13 (72.22)	1.54^b	0.463
rLMCs, median (IQR)	15 (12, 17)	17 (14.7, 19)	16 (14, 18)	4.76^a	0.105
Admission NIHSS score, median (IQR)	12 (7.5, 20.5)	11 (9, 15)	14 (9, 17.5)	2.42^a	0.298
Admission NIHSS score stratification (%)
<13	13 (52)	18 (66.67)	8 (44.44)	4.70^c	0.095
13-19	5 (20)	9 (33.33)	9 (50)
≥ 20	7 (28)	0	1 (5.56)
Vascular risk factors
Hypertension (%)	15 (60)	11 (40.74)	5 (27.78)	4.63^b	0.099
Diabetes (%)	4 (16)	6 (22.22)	5 (27.78)	0.88^b	0.644
Hyperlipidemia (%)	8 (32)	3 (11.11)	7 (38.89)	5.17^b	0.076
Coronary heart disease (%)	3 (12)	8 (29.63)	4 (22.22)	2.41^b	0.30
Congestive heart failure (%)	5 (20)	2 (7.41)	5 (27.78)	3.47^d	0.171
Atrial fibrillation (%)	8 (32)	8 (29.63)	10 (55.56)	3.55^b	0.186
History of ischemic stroke (%)	4 (16)	4 (14.81)	1 (5.56)	1.13^d	0.668
Drinking (%)	1 (4)	2 (7.41)	3 (16.67)	2.08^d	0.428
Smoking (%)	4 (16)	3 (11.11)	6 (33.33)	3.42^d	0.166
Antiplatelet drugs are currently used (%)	1 (4)	0	3 (16.67)	4.62^d	0.059
Statins are currently used (%)	1 (4)	0	3 (16.67)	4.62^d	0.059
Admission serum glucose level, , mmol/l				0.42^a	0.81
Admission systolic blood pressure, , mmHg				2.19^e	0.12
Hospitalization days,				0.95^e	0.39
Time from onset to treatment, median (IQR), min	370 (230.5, 820.5)	154 (125.0, 238.0)	272.5 (183.8, 386.3)	20.80^a	<0.01

Abbreviations: NRT: no reperfusion therapy; IVT: intravenous thrombolysis treatment; EVT: endovascular intervention; rLMCs: regional leptomeningeal score; NIHSS: National Institutes of Health Stroke Scale; SD: standard deviation; IQR: interquartile range. ^aKruskal-Wallis test; ^b test; ^crank sum test; ^dFisher’s exact probability method; ^eANOVA.