Genetic Variants of lncRNA GAS5 Contribute to Susceptibility of Ischemic Stroke among Southern Chinese Population

Table 3

Haplotype frequencies in cases and controls and their relationship to IS risk.

Haplotypes	Case (freq)	Control (freq)	value	value^a	OR (95% CI)
lncRNA GAS5 (rs145204276, rs55829688)
del-T	796 (36.6)	653 (31.2)			1.27 (1.12-1.45)
ins-C	599 (27.6)	626 (29.9)	0.087	0.087	0.89 (0.78-1.02)
ins-T	777 (35.8)	811 (38.8)	0.041	0.062	0.88 (0.78-1.00)

Adjusted for age, gender, smoking, hypertension, diabetes mellitus, and hyperlipidaemia. All those will be ignored in the analysis. ^aFalse discovery rate-adjusted value for multiple hypotheses testing using the Benjamini-Hochberg method. is indicated in bold font. CI: confidence interval; del: rs145204267 AGGCA deletion allele; freq: frequency; GAS5: growth arrest special 5; ins: rs145204267 AGGCA insertion allele; IS: ischemic stroke; lncRNA: long noncoding RNA; OR: odds ratio.