Neutrophil-Lymphocyte Ratio as an Initial Screening Biomarker for Differential Diagnosis of Cushing’s Syndrome from Nonfunctional Adenoma in Patients with an Adrenal Mass

Table 2

Comparison of hormone concentrations, NLR, and PLR in patients with overt CS and AIMCE.

	Overt CS ()	AIMCE ()
8 am serum cortisol (μg/dL)	19.76 (13.79, 25.45)	13.82 (10.51, 16.06)	<0.001
8 am ACTH (pg/mL)	1.23 (0.90, 4.32)	8.43 (4.30, 11.85)	<0.001
NE (×10^9/L)			<0.001
LY (×10^9/L)			<0.001
NLR	4.00 (2.70, 6.18)	2.16 (1.60, 3.07)	<0.001

Results are presented as the or as the median (interquartile range). Abbreviations: ACTH: corticotropin; NE: neutrophil count; LY: lymphocyte count; NLR: neutrophil-lymphocyte ratio; CS: Cushing’s syndrome; AIMCE: adrenal incidentaloma with mild autonomous cortisol excess.