Development of the Binary and Ternary Atorvastatin Solid Dispersions: In Vitro and In Vivo Investigations

Figure 3

DSC thermograms of ATR: untreated atorvastatin; PEG 10000: polyethylene glycol 10000; P188: poloxamer 188; PMB7: physical mixture (ATR : PEG 10000, 1 : 5); BS7: solid dispersion (ATR : PEG 10000, 1 : 5); PMB9: physical mixture (ATR : P188, 1 : 1); BS9: solid dispersion (ATR : P188, 1 : 1); PMT1: physical mixture (ATR : P188 : PEG 10000, 1 : 1 : 5); TS1: solid dispersion (ATR : P188 : PEG 10000, 1 : 1 : 5).