COL3A1 and Its Related Molecules as Potential Biomarkers in the Development of Human Ewing’s Sarcoma

Table 6

Relationship between overall survival and the expression level of COL3A1 researched by univariate and multivariate Cox regression.

Characteristics	Total ()	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Metastasis (yes vs. no)	99	3.679 (1.964-6.892)	<0.001	3.322 (1.419-7.774)	0.006
Tumor region (other and proximal and proximal and distal vs. distal)	63	0.473 (0.198-1.127)	0.091	0.507 (0.212-1.214)	0.127
Age (≥18 vs. <18)	99	0.732 (0.325-1.653)	0.454
COL3A1 (high vs. low)	99	0.512 (0.273-0.960)	0.037	0.522 (0.234-0.865)	0.002
Gender (male vs. female)	99	0.976 (0.520-1.832)	0.940
Primary site progression (yes vs. no)	50	1.769 (0.864-3.626)	0.119