Discovery and Validation of an Epithelial-Mesenchymal Transition-Based Signature in Gastric Cancer by Genomics and Prognosis Analysis

Figure 1

Identification of dysregulated EMT-related genes, biological functions in gastric cancer. (a) Volcano plot depicting the dysregulated EMT-related genes between gastric cancer and normal tissues. -axis represents log fold-change, and -axis indicates -log10 (adjusted value). Red and green dots represent up- and downregulated EMT-related genes in gastric cancer, and black dots represent no significant genes. (b) Heatmaps for dysregulated EMT-related genes between tumor and normal tissues. -axis represents the sample type, and -axis depicts dysregulated EMT-related genes. Red and blue show up- and downregulation in gastric cancer, respectively. (c, d) The top ten GO and KEGG terms enriched by dysregulated EMT-related genes.

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