Overall Prevalence and Prevalence Compared among Psoriasis Treatments of Onychomycosis in Patients with Nail Psoriasis and Fungal Involvement
Table 4
Characteristics of nail psoriasis patients compared among psoriasis treatment regimens.
Number of patients ()
Characteristics
Topical treatment ()
Methotrexate ()
Biologic agents#()
value
Gender, (%)
Female
9 (36.0%)
13 (52.0%)
16 (64.0%)
Male
16 (64.0%)
12 (48.0%)
9 (36.0%)
Age (years),
0.403
Body mass index (kg/m2),
0.042
Concomitant diabetes mellitus, (%)
2 (8.0%)
7 (28.0%)
5 (20.0%)
0.226
Occupation, (%)
Increased risk of hand exposure to water
9 (36.0%)
17 (68.0%)
9 (36.0%)
0.032
Nail severity, median (IQR)
Nail Psoriasis Severity Index score
3.0 (2.0, 4.0)
3.0 (2.0, 4.0)
4.0 (2.0, 4.0)
0.979
Nijmegen-Nail Psoriasis Activity Index score
4.0 (3.0, 5.0)
4.0 (3.0, 5.0)
4.0 (3.0, 5.0)
0.333
Patients with diagnosis of onychomycosis
No
15 (60.0%)
8 (32.0%)
18 (72.0%)
0.014
Yes (right or left hand)
10 (40.0%)
17 (68.0%)
7 (28.0%)
Number of fingernails ()
Characteristics
Topical treatment ()
Methotrexate ()
Biologic agents#()
value
Candida infection of the nails
16 (32.0%)
25 (50.0%)
9 (18.0%)
0.030
Candida colonization of the nails
11 (22.0%)
8 (16.0%)
15 (30.0%)
0.245
Candida infection of the nail folds
7 (14.0%)
8 (16.0%)
6 (12.0%)
0.847
Candida infection of the nails and nail folds
7 (14.0%)
7 (14.0%)
6 (12.0%)
1.000
#Interleukin- (IL-) 17 inhibitors, antitumor necrosis factor, and anti-IL 12/23 were used in 20, 4, and 1 patient, respectively. A value < 0.05 indicates statistical significance. Abbreviations: SD: standard deviation; IQR: interquartile range.
