Preoperative Platelet-to-Lymphocyte Ratio (PLR) for Predicting the Survival of Stage I-III Gastric Cancer Patients with a MGC Component

Table 3

The analysis of prognosis factors in 336 gastric cancer patients with MGC component by univariate and multivariate.

Variables		Univariate analysis		Multivariate analysis
		5-YSR (%)	value	HR (95% CI)	value
Sex	Male	42.2	0.161	—	—
	Female	51.5
Age (years)	<59	54.4	0.001	1.876 (1.361-2.585)	<0.001
	≥59	36.4
R0/R1&2 resection	R0	51.1	<0.001	1.384 (0.927-2.067)	0.112
	R1/R2	14.3
Tumor size (cm)	<5.25	59.9	<0.001	0.884 (0.608-1.286)	0.520
	≥5.25	32.6
pMGC/mMGC	mMGC	47.4	0.211	—	—
	pMGC	39.8
Chemotherapy	Yes	47.1	0.191	—	—
	No	43.1
T-stage	T1	88.9	<0.001	1.289 (0.948-1.753)	0.106
	T2	78.4
	T3	48.8
	T4	35.7
N-stage	N0	80.6	<0.001	1.136 (0.962-1.341)	0.132
	N1	49.2
	N2	40.3
	N3a	29.5
	N3b	17.4
TNM	I+II	78.4	<0.001	2.350 (1.216-4.542)	0.011
	III	30.3
Tumor location	L	54.4	<0.001	1.103 (0.982-1.238)	0.097
	M	38.3
	U	28.6
	LM	34.2
	MU	18.2
	LMU	20.0
Leukocyte	<6.17	49.2	0.077	—	—
	≥6.17	39.7
Neutrophil	<3.31	50.6	0.030	1.174 (0.818-1.684)	0.384
	≥3.31	40.1
Hemoglobin	<125.1	36.9	0.009	1.096 (0.785-1.528)	0.591
	≥125.1	51.3
Fibrinogen	<3.31	52.6	0.005	0.897 (0.655-1.230)	0.500
	≥3.31	36.8
Albumin	<40.1	35.1	<0.001	0.761 (0.553-1.046)	0.092
	≥40.1	53.0
Globulin	<29.2	48.0	0.039	1.520 (1.067-2.165)	0.020
	≥29.2	35.4
NLR	<1.6	55.8	0.002	1.012 (0.662-1.548)	0.956
	≥1.6	39.5
Platelet	<243	51.8	0.010	0.895 (0.619-1.293)	0.554
	≥243	38.0
PLR	<133	55.6	<0.001	1.582 (1.066-2.348)	0.023
	≥133	34.5
Total gastrectomy	Yes	21.7	<0.001	0.537 (0.373-0.772)	0.001
	No	53.7

; 5-YSR = 5-year survival rate; L = lower; M = middle; U = upper; NLR = neutrophil-to-lymphocyte ratio; PLR = platelet-to-lymphocyte ratio; MGC = mucinous gastric carcinoma.