Research Article
Development and Validation of a UPLC-MS/MS Method for the Quantitative Determination and Pharmacokinetic Analysis of Cirsimarin in Rat Plasma
Table 2
Summary of the stability of cirsimarin under various storage conditions (
).
| | Concentration (ng/mL) | Autosampler (4°C, 12 h) | Ambient (2 h) | –20°C (30 d) | Freeze-thaw | | Accuracy | RSD | Accuracy | RSD | Accuracy | RSD | Accuracy | RSD |
| | 4 | 106.8 | 5.1 | 101.8 | 5.6 | 106.8 | 7.8 | 104.4 | 13.8 | | 180 | 99.0 | 4.2 | 97.1 | 9.9 | 99.0 | 11.1 | 92.3 | 5.6 | | 2500 | 106.4 | 6.8 | 101.5 | 5.4 | 106.4 | 5.7 | 92.9 | 3.4 |
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