Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model

Figure 3

Results of open field and novel object recognition tests. (a) Mice were placed in an open field chamber, and the patterns of movement were analyzed ( per group). IZ: inner zone. (b) Mice were placed in a chamber where a familiar and a novel object were each located at different corners. No. Entry to NO/FO (%): the number of entries to the novel object area compared to the entries to the familiar object area; discrimination index (%): the level of recognizing, remembering, and discriminating the novel object from the familiar object. ( and 16 for sham, BCAO, and H2, respectively). NO: novel object; FO: familiar object; BCAO: bilateral common carotid artery occlusion. , , and ; n.s: not significant.

(a)

(b)