Peptidome Analysis of Pancreatic Tissue Derived from T1DM Mice: Insights into the Pathogenesis and Clinical Treatments of T1DM

Figure 1

Differently expressed peptides between T1DM and normal mice. (a) Of the 1,063 nonredundant peptides, 106 peptides were significantly differentially expressed in the T1DM mice ( and ), including 43 upregulated and 63 downregulated peptides. Hierarchical clustering showed significant differences in expression between the two groups. The twenty upregulated (b) and downregulated (c) peptides with the highest fold changes were displayed. : control; T1DM: type 1 diabetes mellitus; high expression: red; low expression: green.

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