Research Article

Effectiveness and Safety of Low Dose of Tenofovir Disoproxil Fumarate in Malagasy Patients with Chronic Hepatitis B

Table 3

Virological and biochemical response after low dose of TDF in naïve and experienced patients.

VariablesNA-naïve ()NA-experienced, viraemic ()NA-experienced, nonviraemic ()

3 months
 CVR, (%)11 (73.3)15 (75)10 (100)
 ALT normalization, (%)11 (73.3)12 (60)6 (60)
6 months
 CVR, (%)12 (80)19 (95)10 (100)
 ALT normalization, (%)12 (80)17 (85)10 (100)
12 months
 CVR, (%)14 (93.3)19 (95)10 (100)
 ALT normalization, (%)15 (100)20 (100)10 (100)

CVR: complete virological response; ALT: alanine aminotransferase; NA: nucleos(t)ide analog.