Research Article

Ameliorating Effect of Malva neglecta Wallr on Obesity and Diabetes in Wistar Rats: A Mechanistic Study

Table 3

The effect of Malva neglecta extract on leptin, lipid profile, HbA1c, and insulin level in diabetic obese rats.

Treatment groupsLeptin (ug/ml)Triglycerides (mmol/L)Cholesterol (mmol/L)LDL (mmol/L)HDL (mmol/L)HbA1c (%)Insulin (μU/ml)

Normal control
Disease control
Metformin treatment
MNME 250 mg/kg
MNME 500 mg/kg
MNME 750 mg/kg

Data were shown as (). , , , and showed significantly different in comparison to the disease control group. MNME: methanolic extract of Malva neglecta; LDL: low density; HDL: high-density lipoprotein; HbA1c: glycosylated hemoglobin.