SARS-CoV-2 Induces Expression of Cytokine and MUC5AC/5B in Human Nasal Epithelial Cell through ACE 2 Receptor

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="8"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Spike protein<br/>Receptor binding domain</td><td class="align_center" colspan="7">Gene</td></tr><tr class="thead"><td class="align_center">ACE2</td><td class="align_center">TMPRSS2</td><td class="align_center">IL-1<i>β</i></td><td class="align_center">IL-6</td><td class="align_center">IL-8</td><td class="align_center">MUC5AC</td><td class="align_center">MUC5B</td></tr><tr><td class="thead-hr" colspan="8"><hr/></td></tr><tr><td class="align_left">0 <i>μ</i>g/ml</td><td class="align_center">1.000 (0.379)</td><td class="align_center">1.000 (0.229)</td><td class="align_center">1.000 (0.679)</td><td class="align_center">1.000 (0.534)</td><td class="align_center">1.000 (0.309)</td><td class="align_center">1.000 (0.270)</td><td class="align_center">1.000 (0.205)</td></tr><tr><td class="align_left">5 <i>μ</i>g/ml</td><td class="align_center">2.146 (0.285)</td><td class="align_center">1.731 (0.422)</td><td class="align_center">3.157 (0.255)</td><td class="align_center">4.471 (0.325)</td><td class="align_center">3.858 (0.410)</td><td class="align_center">2.110 (0.125)</td><td class="align_center">1.566 (0.310)</td></tr><tr><td class="align_left">10 <i>μ</i>g/ml</td><td class="align_center">4.518 (0.276)</td><td class="align_center">1.308 (0.397)</td><td class="align_center">7.727 (0.296)</td><td class="align_center">12.810 (0.351)</td><td class="align_center">6.568 (0.527)</td><td class="align_center">2.052 (0.251)</td><td class="align_center">1.764 (0.327)</td></tr><tr class="table-tr"><td colspan="8"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

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BioMed Research International

tab2

Table 2

Table 2: SARS-CoV-2 Induces Expression of Cytokine and MUC5AC/5B in Human Nasal Epithelial Cell through ACE 2 Receptor 