Synergistic Impacts of Alpinia oxyphylla Seed Extract and Allopurinol against Experimental Hyperuricemia

Figure 1

Effects of allopurinol, Alpinia oxyphylla seed extract (AE), and their combination on (a) serum urate, (b) urine urate, and (c) fractional renal clearance of urate in hyperuricemic rats. per group. NC: normal control; PO group: induced with potassium oxonate; AP: allopurinol (1 mg/kg); AE (200 mg/kg); AP + AE: AP (1 mg/kg) plus allopurinol (200 mg/kg). # and ### compared with the NC group; and compared with the PO group; $$$ compared with the AP or AE groups.

(a)

(b)

(c)