Research Article

Developing a Diagnostic Model to Predict the Risk of Asthma Based on Ten Macrophage-Related Gene Signatures

Figure 1

Screening of DEGs between AS and normal samples. (a, b) PCA diagrams before and after removing the batch effect on samples from the two datasets. Black and red dots represent samples in GSE137268 and GSE148004, respectively. (c) The volcano plot showed 1,189 DEGs between AS and the control groups screened from combined samples with the and criteria. The -axis indicates the value of log2FC, while the -axis indicates the FDR value. The green and orange dots represent downregulated and upregulated DEGs, respectively, with statistical significance. (d) Heatmap based on the expression levels of DEGs.