Cirsium japonicum var. Maackii Improves Cognitive Impairment under Amyloid Beta_25-35-Induced Alzheimer’s Disease Model

Figure 2

Effect of ECJM on T-maze test. (1) Sham group: injection of 0.9% NaCl and oral administration of water. (2) Control group: injection of Aβ_25-35 and oral administration of water. (3) ECJM50 group: injection of Aβ_25-35 and oral administration of ECJM (50 mg/kg/day). (4) ECJM100 group: injection of Aβ_25-35 and oral administration of ECJM (100 mg/kg/day). (5) Donepezil group: injection of Aβ_25-35 and oral administration of donepezil (5 mg/kg/day). Values are the . One-way ANOVA was used to compare the mean values of groups, followed by Duncan’s multiple-range test post hoc. Different alphabet letters (a, b) indicate statistically significant difference (). Mean values with the same letter are not significantly different. The asterisk () represents the significant difference in space perceptive abilities with old and new routes by Student’s -test ().