Identification of Small Nucleolar RNA SNORD60 as a Potential Biomarker and Its Clinical Significance in Lung Adenocarcinoma

Table 1

Cox regression for overall survival analysis.

Variables	Univariate cox		Multivariate cox
	HR (95% CI)	value	HR (95% CI)	value
Age (years)
≥65	1
<65	0.872 (0.614-1.238)	0.444
Gender
Female	1
Male	1.046 (0.739-1.481)	0.798
Stage
I	1
II	2.159 (1.386-3.363)	0.001^a
III	3.253 (2.083-5.080)	≤0.001^a
IV	3.145 (1.692-5.844)	≤0.001^a
T
T1	1
T2	1.789 (1.122-2.853)	0.015^a	1.590 (0.995-2.543)	0.053
T3	4.726 (2.505-8.917)	≤0.001^a	4.151 (2.150-8.014)	≤0.001^a
T4	3.133 (1.522-6.452)	0.002^a	2.149 (1.001-4.613)	0.050
N
N0	1
N1	2.293 (1.519-3.463)	≤0.001^a	2.220 (1.457-3.381)	≤0.001^a
N2	3.209 (2.073-4.970)	≤0.001^a	2.584 (1.641-4.070)	≤0.001^a
N3	3.795e-07 (0.000-inf)	0.995	2.360e-07 (0.000-inf)	0.995
M
M0	1
M1	1.965 (1.104-3.495)	0.022^a	1.708 (0.927-3.148)	0.086
SNORD60_group^b
High	1
Low	1.140 (0.802-1.621)	0.465

Abbreviation: CI: confidence interval; inf: infinity. ^a. ^bCutoff threshold of SNORD60 expression is median value in all patients.