Combination of Goniothalamin and Sol-Gel-Derived Bioactive Glass 45S5 Enhances Growth Inhibitory Activity via Apoptosis Induction and Cell Cycle Arrest in Breast Cancer Cells MCF-7

Figure 10

Activation of caspase-8, caspase-9, and caspase-3/7 in MCF-7 cells after 48 hours. All experiments were performed in triplicate, and the data is represented by . Comparisons between the groups of different treatments were done by using 1-way ANOVA, followed by the Bonferroni posttest for multiple comparisons. The significant difference between the treated and untreated cells is marked as , , and , whereas the significant difference between GTN- and GTN-BG-treated cells is represented as ⁺, ⁺⁺, and ⁺⁺⁺.