Research Article

[Retracted] Identification of Molecular Biomarkers and Key Pathways for Esophageal Carcinoma (EsC): A Bioinformatics Approach

Table 3

Gene Ontology analysis of upregulated DEGs using DAVID functional tools.

CategoryGO IDGO termCount% value

BPGO:0045892Negative regulation of transcription, DNA-templated220.0359890.001478
BPGO:0046513Ceramide biosynthetic process50.0081790.001541
BPGO:0016567Protein ubiquitination170.027810.00305
BPGO:0051726Regulation of cell cycle90.0147230.003954
BPGO:0048013Ephrin receptor signaling pathway70.0114510.008317
BPGO:0016477Cell migration100.0163590.008953
BPGO:0000045Autophagosome assembly50.0081790.009555
BPGO:0045893Positive regulation of transcription, DNA-templated200.0327170.009702
BPGO:0055007Cardiac muscle cell differentiation40.0065430.017191
BPGO:0051865Protein autoubiquitination50.0081790.018845
CCGO:0005789Endoplasmic reticulum membrane370.0605271.84E-05
CCGO:0005654Nucleoplasm830.1357768.75E-05
CCGO:0005634Nucleus1360.2224777.26E-04
CCGO:0005802Trans-Golgi network100.0163590.001509
CCGO:0031965Nuclear membrane130.0212660.002026
CCGO:0005622Intracellular390.0637980.013664
CCGO:0005737Cytoplasm1230.2012110.015049
CCGO:0005829Cytosol800.1308690.036397
CCGO:0005671Ada2/Gcn5/Ada3 transcription activator complex30.0049080.038709
CCGO:0000139Golgi membrane190.0310810.046953
MFGO:0005515Protein binding2370.3876981.25E-08
MFGO:0003677DNA binding560.0916085.22E-04
MFGO:0003684Damaged DNA binding70.0114510.002026
MFGO:0004842Ubiquitin-protein transferase activity160.0261740.004151
MFGO:0061630Ubiquitin protein ligase activity110.0179940.00625
MFGO:0005070SH3/SH2 adaptor activity60.0098150.006276
MFGO:0008565Protein transporter activity60.0098150.017551
MFGO:0017137Rab GTPase binding80.0130870.022939
MFGO:0003676Nucleic acid binding310.0507120.02606
MFGO:0032794GTPase activating protein binding30.0049080.03379

GO: Gene Ontology; BP: biological process; CC: cellular component; MF: molecular function.