[Retracted] Identification of Molecular Biomarkers and Key Pathways for Esophageal Carcinoma (EsC): A Bioinformatics Approach

Table 5

Pathway enrichment analysis of (a) upregulated and (b) downregulated DEGs using DAVID functional tools.

Pathway term	Benjamini	value	Source
(A) Upregulated
Protein export	0.169923	9.40E-04	KEGG
Axon guidance	0.284819	0.00338	KEGG
RHO GTPases Activate Formins	0.959243	0.007813	REACTOME
HATs acetylate histones	0.882682	0.010449	REACTOME
Sphingolipid metabolism	0.583473	0.013182	KEGG
Pathogenic Escherichia coli infection	0.580496	0.017396	KEGG
Golgi associated vesicle biogenesis	0.975818	0.026998	REACTOME
ErbB signaling pathway	0.671562	0.027725	KEGG
Sphingolipid signaling pathway	0.637004	0.030241	KEGG
XBP1(S) activates chaperone genes	0.956916	0.030359	REACTOME
Lysosome	0.593513	0.031324	KEGG
The information-processing pathway at the IFN-beta enhancer	0.978374	0.034876	BIOCARTA
Activation of RAC1	0.961151	0.039023	REACTOME
Signaling of hepatocyte growth factor receptor	0.890962	0.040208	BIOCARTA
Epithelial cell signaling in helicobacter pylori infection	0.654812	0.042066	KEGG
(B) Downregulated
L13a-mediated translational silencing of ceruloplasmin expression	3.71E-07	4.17E-10	REACTOME
Formation of a pool of free 40S subunits	4.51E-07	5.06E-10	REACTOME
GTP hydrolysis and joining of the 60S ribosomal subunit	4.84E-07	5.43E-10	REACTOME
Ribosome	3.48E-07	1.26E-09	KEGG
Peptide chain elongation	4.55E-06	5.11E-09	REACTOME
Selenocysteine synthesis	1.04E-05	1.17E-08	REACTOME
Eukaryotic translation termination	1.37E-05	1.53E-08	REACTOME
Viral mRNA translation	1.99E-05	2.24E-08	REACTOME
Nonsense mediated decay (NMD) independent of the exon junction complex (EJC)	2.30E-05	2.58E-08	REACTOME
SRP-dependent cotranslational protein targeting to membrane	3.08E-04	3.45E-07	REACTOME
Nonsense mediated decay (NMD) enhanced by the exon junction complex (EJC)	3.78E-04	4.24E-07	REACTOME
Formation of the ternary complex, and subsequently, the 43S complex	0.008265	9.31E-06	REACTOME
Ribosomal scanning and start codon recognition	0.012429	1.40E-05	REACTOME
Translation initiation complex formation	0.012429	1.40E-05	REACTOME
Chemokine	0.001886	3.85E-05	BBID