Relationship between Neutrophil Gelatinase-Associated Lipocalin, Eosinophil Cationic Protein, Cytokines, and Atopic Sensitization in Patients with Allergic Diseases

Table 7

Relationship between NGAL, ECP, cytokines, and allergy-related parameters.

Parameters	Multivariate regression analysis ()
	NGAL	ECP
IL-5	0.121 (0.204)	0.264 (<0.001)
TNF-α	0.332 (<0.001)	0.145 (0.124)
TGF-β1	0.285 (<0.001)	0.157 (0.116)
ECP	0.114 (0.213)	NA
ECP/Eo ratio	0.136 (0.152)	NA
hsCRP	0.413 (<0.001)	0.136 (0.129)
tIgE	0.092 (0.307)	0.327 (<0.001)
sIgE	0.105 (0.221)	0.289 (<0.001)

Data are expressed as standardized β (P value). Adjusted for age, sex, BMI, SBP, and current smoking. IL-5: interleukin-5; TNF-α: tumor necrosis factor-α; TGF-β1: transforming growth factor-β1; ECP: eosinophil cationic protein; ECP/Eo ratio: ECP/eosinophil count ratio; hsCRP: high-sensitivity C-reactive protein; tIgE: total immunoglobulin E; sIgE: specific IgE; NGAL: neutrophil gelatinase-associated lipocalin; and NA: not applicable.