Research Article
Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats
Table 1
Antisecretory effects of aqueous and ethanolic extracts of Nauclea diderrichii on castor oil-induced diarrhea.
| Treatments | Doses (mg/kg) | Onset time (min) | Total stool frequency | Diarrheal stool frequency | Inhibition (%) | Water content (%) |
| DW (Neu) | 1 ml/100 g | | | | — | | DW (Neg) | 1 ml/100 g | c | c | c | — | c | DMSO 5% (Neg) | 1 ml/100 g | c | c | c | — | c | Lop (Pos) | 2.5 | | | | 100 | | Aqueous extract | 100 | | | | 70 | c | 200 | | | | 76.80 | c | 300 | | | | 93.40 | | Ethanolic extract | 100 | c | | | 78.59 | c | 200 | | | | 82.23 | | 300 | | | | 78.59 | |
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