Research Article

Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats

Table 1

Antisecretory effects of aqueous and ethanolic extracts of Nauclea diderrichii on castor oil-induced diarrhea.

TreatmentsDoses (mg/kg)Onset time (min)Total stool frequencyDiarrheal stool frequencyInhibition (%)Water content (%)

DW (Neu)1 ml/100 g
DW (Neg)1 ml/100 gcccc
DMSO 5% (Neg)1 ml/100 gcccc
Lop (Pos)2.5100
Aqueous extract10070c
20076.80c
30093.40
Ethanolic extract100c78.59c
20082.23
30078.59