Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats

Table 3

Effect of yohimbine and glibenclamide on antidiarrheal activity of aqueous extract of Nauclea diderrichii on castor oil-induced secretory diarrhea.

Treatments	Onset (min)	Total stool frequency	Diarrheal stool frequency	Inhibition (%)
DW (Neu)				—
DW (Neg)	^c	^c	^c	—
Lop (Pos)				100
AE 300				84.42
GLIB (1 mg/kg)+AE 300				49.91
YOHI (1 mg/kg)+AE 300				81.24
GLIB (1 mg/kg)		^c	^c	18.76
YOHI (1 mg/kg)				28.14