Research Article

Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats

Table 5

Effects of aqueous and ethanolic stem bark extracts of Nauclea diderrichii on castor oil-induced motility.

TreatmentsDose (mg/kg)Total length of intestine (cm)Traveled distance by charcoal (cm)Peristaltic index (%)% inhibition

DW (Neu)1 ml/100 g
DW (Neg)1 ml/100 g
DMSO (Neg)1 ml/100 g
Atropine150.67
Aqueous extract10029.02
20033.56
30031.26
Ethanolic extract10037.06
20037.94
30040.59