Research Article

Antisecretory and Spasmolytic Activities of Aqueous and Ethanolic Stem Bark Extracts of Nauclea diderrichii in Wistar Rats

Table 6

Effects of aqueous and ethanolic stem bark extracts of Nauclea diderichii on carbachol-induced intestinal motility.

TreatmentsDose (mg/kg)Total length of intestine (cm)Traveled distance by charcoal (cm)Peristaltic index (%)% inhibition

DW (Neu)1 ml/100 g
DW (Neg)1 ml/100 g
DMSO (Neg)1 ml/100 g
Atropine139.71
Aqueous extract10021.98
20036.00
30034.92
Ethanolic extract100a30.85
200bb27.78
300aa30.82