Metabolomics of Esophageal Squamous Cell Carcinoma Tissues: Potential Biomarkers for Diagnosis and Promising Targets for Therapy

Table 3

KEGG pathway topology analysis detailed table.

Pathway description	Match-status (|)	Impact value	value corrected
Tryptophan metabolism	3|56	0.2481	0.01486
Glycerophospholipid metabolism	3|48	0.1101	0.01284
Sphingolipid metabolism	3|21	0.0691	0.001685
Phenylalanine metabolizes	2|46	0.03904	0.08317
Phenylalanine, tyrosine, and tryptophan biosynthesis	2|33	0.03785	0.05449
Purine metabolism	2|81	0.02886	0.1624
Steroid hormone synthesis	2|89	0.01454	0.1506

Note: match-status indicates the situation that which the metabolites are involved in the pathway. indicates the number of metabolites involved in the pathway in the current metabolic set, and indicates the total number of metabolites in the current pathway; impact value: the comprehensive importance score of the pathway, with a total score of 1; value corrected value is the corrected of the enrichment significance value of metabolites involved in the pathway.