Research Article

Whole-Transcriptome Sequencing Combined with High-Dimensional Proteomic Technologies Reveals the Potential Value of miR-135b-5p as a Biomarker for Hepatocellular Carcinoma

Figure 4

Distinct tumor differentiation extent between the miR-135b-5p-high and miR-135b-5p-low groups. (a) Representative IMC images show the expression of hepatocyte-specific markers in miR-135b-5p-high (top left) and miR-135b-5p-low groups (bottom left); box plots show the expression of hepatocyte-specific markers in the miR-135b-5p-high and miR-135b-5p-low groups (right). (b) Images of hematoxylin and eosin staining show differentiated degree of tumor cells in the miR-135b-5p-high and miR-135b-5p-low groups, exhibited by different magnification (top: ×100 and bottom: ×200). (c) Representative IMC images show the expression of YAP1 and CK19 in the miR-135b-5p-high (top left) and miR-135b-5p-low groups (bottom left); box plots show the expression of YAP1 and CK19 in the miR-135b-5p-high and miR-135b-5p-low groups (right). (d) Representative IMC images show the expression of EMT-related markers in the miR-135b-5p-high (top left) and miR-135b-5p-low groups (bottom left); box plots show the expression of EMT-related markers in the miR-135b-5p-high and miR-135b-5p-low groups (right). , , and .
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