BioMed Research International

Molecular Biomarkers: Tools of Medicine


Publishing date
15 Nov 2013
Status
Published
Submission deadline
28 Jun 2013

1Edward Waters College, 1658 Kings Road, Jacksonville, FL 32209, USA

2Department of Biological Sciences, Alabama State University, Room no. 325, Life Science Building, 1627 Hall Street, Montgomery, AL 36104, USA

3College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1520 M L King Boulevard, Tallahassee, FL 32307, USA

4Laboratory of General Physiology, Department of Biological and Environmental Sciences and Technologies, University of Salento, Via Provinciale Lecce-Monteroni, 73100 Lecce, Italy

5Department of Translational Science and Molecular Medicine, MSU College of Human Medicine and Van Andel Institute, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA


Molecular Biomarkers: Tools of Medicine

Description

In medicine, a biomarker can be a substance that is introduced into an organism as a means to examine organ function. It can also be a substance whose detection indicates a particular disease state. More specifically, a biomarker indicates a change in expression or state of a protein that correlates with the risk or progression of a disease. There has been an explosion in the discovery of biomarkers for diagnosis, disease monitoring, and prognostic evaluation. Molecular biomarkers are emerging as the key indices for the management of patients with significant diseases. Motivated by the systematic effort to define the human genome, the creation of rapid analytic technologies for evaluating nucleic acids and proteins has provided the technological “boom ” for the development of “molecular biomarkers.” Collaboration and cooperation between stakeholders involved in biomarker development, application, and regulation may be the most expeditious route toward the translation of laboratory discovery into patient management.

The main focus of this special issue will be on the advances in our understanding of how biological processes interact, thus enabling such technologies as genomics, proteomics, metabolomics, and lipidomics-combined with drug discovery and development, high-throughput screening, and in silico drug development, place science on the threshold of innovative management. This special issue will become an international forum for researchers to summarize the most recent developments and ideas in the field, with a special emphasis given to the expeditious path toward the translation of laboratory discovery into patient management within the last five years. Potential topics include, but are not limited to:

  • Identification of biomarkers
  • Disease-related biomarkers
  • Drug-related biomarkers
  • Biomarkers in drug development
  • Technological advances
  • Discovery of molecular biomarkers and elucidation of their role
  • Imaging biomarkers and potential disadvantages
  • Formalization and approval of their application in modern medicine

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biotechnology/mbtm/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 782941
  • - Research Article

Distribution of ABO Blood Group and Major Cardiovascular Risk Factors with Coronary Heart Disease

Santanu Biswas | Pradip K. Ghoshal | ... | Nripendranath Mandal
  • Special Issue
  • - Volume 2013
  • - Article ID 108951
  • - Research Article

Immunomodulatory Effect of Continuous Venovenous Hemofiltration during Sepsis: Preliminary Data

Giuseppe Servillo | Maria Vargas | ... | Bruno Memoli
  • Special Issue
  • - Volume 2013
  • - Article ID 321213
  • - Review Article

Acetylcholinesterase as a Biomarker in Environmental and Occupational Medicine: New Insights and Future Perspectives

Maria Giulia Lionetto | Roberto Caricato | ... | Trifone Schettino
  • Special Issue
  • - Volume 2013
  • - Article ID 416534
  • - Research Article

Polyisoprenylated Methylated Protein Methyl Esterase Is Both Sensitive to Curcumin and Overexpressed in Colorectal Cancer: Implications for Chemoprevention and Treatment

Felix Amissah | Randolph Duverna | ... | Nazarius S. Lamango
  • Special Issue
  • - Volume 2013
  • - Article ID 130362
  • - Review Article

Emerging Therapeutic Biomarkers in Endometrial Cancer

Peixin Dong | Masanori Kaneuchi | ... | Noriaki Sakuragi
  • Special Issue
  • - Volume 2013
  • - Article ID 913179
  • - Research Article

Mouse Prostate Epithelial Luminal Cells Lineage Originate in the Basal Layer Where the Primitive Stem/Early Progenitor Cells Reside: Implications for Identifying Prostate Cancer Stem Cells

Jianjun Zhou | Lionel Feigenbaum | ... | Clayton Yates
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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