BioMed Research International

Biomolecular Networks and Human Diseases


Publishing date
30 May 2014
Status
Published
Submission deadline
10 Jan 2014

1Division of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK, Canada S7N 5A9

2Collaborative Research Center for Innovative Mathematical Modelling, Institute of Industrial Science, University of Tokyo, Tokyo 153-8505, Japan

3School of Information Science and Engineering, Central South University, Changsha, Hunan, China

4Department of Computer Science, University of Calgary, Calgary, AB, Canada


Biomolecular Networks and Human Diseases

Description

Now, it is widely acknowledged that genetically caused diseases or disorders (e.g., cancer, AIDS, and obesity) stem from the dysfunction of molecular biological systems, not only their isolated components (e.g., genes, proteins, and metabolites). Molecular biological systems typically include gene regulatory networks, protein-protein interaction networks, metabolic networks, and signal transduction networks. With advances in high-throughput measurement techniques such as microarray, ChIP-chip, yeast two-hybrid analysis, and mass spectrometry, large-scale biological data have been and will continuously be produced. Such data contain insightful information for understanding the mechanism of molecular biological systems and have proved to be useful in diagnosis, treatment, and drug design for genetically inherited diseases or disorders.

For this special issue, we strongly encourage authors to submit their original studies in modeling/construction, analysis, synthesis, and control of disease-related biomolecular networks. Potential topics include, but are not limited to:

  • Biomolecular network modeling/construction
  • Prediction of disease-causing molecules from biomolecular networks
  • Dynamic analysis of biomolecular networks
  • Identification of drug targets from biomolecular networks
  • Parameter estimation of nonlinear dynamic molecular systems
  • Controllability and observability of biomolecular networks
  • Specific disease-related molecular networks
  • Therapeutic molecular networks
  • Disease-related molecular (e.g., protein, transcriptome and ncRNA, and metabolite) complex or functional module detection
  • Application tools for biomolecular network visualization and analysis

Before submission, authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/bioinformatics/bnhd/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 363717
  • - Editorial

Biomolecular Networks and Human Diseases

FangXiang Wu | Luonan Chen | ... | Reda Alhajj
  • Special Issue
  • - Volume 2014
  • - Article ID 968173
  • - Research Article

ABC and IFC: Modules Detection Method for PPI Network

Xiujuan Lei | Fang-Xiang Wu | ... | Jie Zhao
  • Special Issue
  • - Volume 2014
  • - Article ID 375262
  • - Research Article

Identifying Dynamic Protein Complexes Based on Gene Expression Profiles and PPI Networks

Min Li | Weijie Chen | ... | Yi Pan
  • Special Issue
  • - Volume 2014
  • - Article ID 278956
  • - Research Article

A Network Biology Approach to Discover the Molecular Biomarker Associated with Hepatocellular Carcinoma

Liwei Zhuang | Yun Wu | ... | Yili Fu
  • Special Issue
  • - Volume 2014
  • - Article ID 676724
  • - Research Article

Multiple Regression Analysis of mRNA-miRNA Associations in Colorectal Cancer Pathway

Fengfeng Wang | S. C. Cesar Wong | ... | Benjamin Y. M. Yung
  • Special Issue
  • - Volume 2014
  • - Article ID 534821
  • - Research Article

Network of microRNAs-mRNAs Interactions in Pancreatic Cancer

Elnaz Naderi | Mehdi Mostafaei | ... | Ashraf Mohamadkhani
  • Special Issue
  • - Volume 2014
  • - Article ID 171892
  • - Research Article

Pathway-Driven Discovery of Rare Mutational Impact on Cancer

TaeJin Ahn | Taesung Park
  • Special Issue
  • - Volume 2014
  • - Article ID 189590
  • - Research Article

Mining Seasonal Marine Microbial Pattern with Greedy Heuristic Clustering and Symmetrical Nonnegative Matrix Factorization

Fei Liu | Shao-Wu Zhang | ... | Chen Zhou
  • Special Issue
  • - Volume 2014
  • - Article ID 196034
  • - Research Article

Syn-Lethality: An Integrative Knowledge Base of Synthetic Lethality towards Discovery of Selective Anticancer Therapies

Xue-juan Li | Shital K. Mishra | ... | Jie Zheng
  • Special Issue
  • - Volume 2014
  • - Article ID 354539
  • - Research Article

A Novel Algorithm for Detecting Protein Complexes with the Breadth First Search

Xiwei Tang | Jianxin Wang | ... | Yi Pan
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision77 days
Acceptance to publication52 days
CiteScore2.410
Impact Factor2.197
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