Table of Contents Author Guidelines Submit a Manuscript

DNA Damage and Oxidative Stress in Human Disease

Call for Papers

Some genotoxic conditions can produce a wide variety of effects on human health. Some of these effects appear immediately, whereas others do not become evident until much later. Several chronic diseases have been studied for its mechanism of perpetuation of clinical complications and the development of secondary diseases such as cancer. Oxidative stress and, therefore, genomic instability have gained growing attention in understanding this process.

Genetic instability due to increased DNA damage has an important impact on the pathogenesis of chronic disease. Common effects of DNA damage are interference with fundamental cell features such as cell differentiation, DNA repair, epigenetic marking, cell cycle regulation, and apoptosis. Potential topics include, but are not limited to:

  • Oxidative stress markers
  • DNA damage detection techniques
  • Free radicals in human disease
  • DNA damage in human disease
  • Inflammation and oxidative stress
  • Chromosome instability syndromes
  • Epigenetic modifications and human disease
  • Antioxidants and DNA protectors

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Manuscript DueFriday, 5 April 2013
First Round of ReviewsFriday, 28 June 2013
Publication DateFriday, 23 August 2013

Lead Guest Editor

  • Sharbel Weidner Maluf, Medical Genetics Service, Hospital de de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, 90035-903 Porto Alegre, RS, Brazil

Guest Editors

  • Daniel Prá, Santa Cruz do Sul University (UNISC), Santa Cruz do Sul, RS, Brazil
  • Vanina Heuser, University of Turku, Turku, Finland
  • Norma Possa Marroni, Laboratory of Experimental Pathology, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil; Laboratory of Oxidative Stress and Antioxidants, ULBRA, Canoas, RS, Brazil