BioMed Research International

Aging: Mitigation and Intervention Strategies


Publishing date
28 Nov 2014
Status
Published
Submission deadline
11 Jul 2014

Lead Editor

1School of Medicine, Fu Jen Catholic University, New Taipei, Taiwan

2School of Biology, University of Costa Rica, Mercedes, Costa Rica

3Department of Pharmacology, School of Basic Medical Science, Peking University, Beijing, China

4Moffitt Cancer Center, Tampa, FL, USA

5School of Pharmacy, University of Nottingham, Nottingham, UK


Aging: Mitigation and Intervention Strategies

Description

Aging is a natural process of life. The causes of aging may come from different sources, both internally and externally. Cellular aging may lead to organ dysfunction during this complicate, irreversible process. Decreased estrogen and melatonin levels may put menopausal women at a higher risk of skin aging, osteoporosis, and cardiovascular disease. Shortening of telomeres during each cell division may lead to cell death when the cell stops dividing while cell's telomeres shrink to a critical minimum size, which is one of the causes found in the degeneration of our vision, memory, and immune system. Another contributor to the aging process is oxidative stress. Increased reactive oxygen species (ROS) levels caused by environmental pollution, ionizing radiation, food additives, and so forth may mutates our genes and induce harmful effects on our cells, such as oxidations of lipid, amino acids in proteins, and inactivate specific enzymes, which can be a causal factor of cancer development and premature aging. Skin photoaging and some degenerative diseases such as Alzheimer's disease are some of the examples accompanied by oxidative stress. In order to live healthy while we grow old, a healthy eating and life style is crucial. Meanwhile, scientists spend lot of effort trying to investigate ways to support healthy aging and prevent or delay the onset of age-related disease and decline. Many natural ingredients are also found to be beneficial, such that flavonoids may help fight oxidative stress and isoflavones may act as estrogen to decrease related symptoms and diseases in menopausal women.

The goal of this special issue is to collect information on the mechanism of aging and idea on how to mitigate, delay, or treat age-related decline and diseases and particularly focus on the roles of hormone, ROS, inflammation, gene, and immunity in aging and antiaging, as well as investigations of natural products and medications related to antiaging, thus promoting a healthy aging from different aspects. Both original papers and reviews are welcome. Potential topics include, but are not limited to:

  • Recent developments in aging and antiaging
  • Role of hormone in aging and antiaging
  • Role of ROS and inflammation in aging and antiaging
  • Role of gene and immunity in aging and antiaging
  • Role of natural product in antiaging
  • Recent advances in antiaging drug

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/pharmacology/apis/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 276539
  • - Editorial

Aging: Mitigation and Intervention Strategies

Chi-Feng Hung | Jorge Azofeifa-Navas | ... | Nicole Clarke
  • Special Issue
  • - Volume 2015
  • - Article ID 235709
  • - Review Article

A Low-Dose Combination of Fluvastatin and Valsartan: A New “Drug” and a New Approach for Decreasing the Arterial Age

Miodrag Janić | Mojca Lunder | Mišo Šabovič
  • Special Issue
  • - Volume 2015
  • - Article ID 620643
  • - Clinical Study

Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review

Salvatore Parisi | Pietro Corsa | ... | Guido Valle
  • Special Issue
  • - Volume 2015
  • - Article ID 906039
  • - Research Article

The Differential Effects of a Selective Kappa-Opioid Receptor Agonist, U50488, in Guinea Pig Heart Tissues

Chi-Feng Hung | Hsin-Ju Li | ... | Ming Jai Su
  • Special Issue
  • - Volume 2015
  • - Article ID 425380
  • - Research Article

Curcumin Mitigates Accelerated Aging after Irradiation in Drosophila by Reducing Oxidative Stress

Ki Moon Seong | Mira Yu | ... | Kyung-Jin Min
  • Special Issue
  • - Volume 2015
  • - Article ID 564738
  • - Clinical Study

Effect of Supplemental Lutein and Zeaxanthin on Serum, Macular Pigmentation, and Visual Performance in Patients with Early Age-Related Macular Degeneration

Yang-Mu Huang | Hong-Liang Dou | ... | Xiao-Ming Lin
  • Special Issue
  • - Volume 2014
  • - Article ID 297293
  • - Review Article

Natural Compounds and Aging: Between Autophagy and Inflammasome

Shih-Yi Chuang | Chih-Hung Lin | Jia-You Fang
  • Special Issue
  • - Volume 2014
  • - Article ID 151479
  • - Research Article

GHK and DNA: Resetting the Human Genome to Health

Loren Pickart | Jessica Michelle Vasquez-Soltero | Anna Margolina
  • Special Issue
  • - Volume 2014
  • - Article ID 140165
  • - Review Article

Superoxide Dismutase 1 Loss Disturbs Intracellular Redox Signaling, Resulting in Global Age-Related Pathological Changes

Kenji Watanabe | Shuichi Shibuya | ... | Takahiko Shimizu
  • Special Issue
  • - Volume 2014
  • - Article ID 695797
  • - Research Article

Inhibition of Peroxisome Proliferator-Activated Receptor Gamma Prevents the Melanogenesis in Murine B16/F10 Melanoma Cells

Jiun-Han Chen | Junn-Liang Chang | ... | Mei-Jung Chen
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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