BioMed Research International

Myocardial Diseases: Current Views on Etiopathogenesis, Diagnostic Modalities, and Therapeutic Options


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Published

Lead Editor

1Charles University in Prague, Prague, Czech Republic

2McMaster University, Hamilton, Canada

3King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia


Myocardial Diseases: Current Views on Etiopathogenesis, Diagnostic Modalities, and Therapeutic Options

Description

Cardiomyopathies are currently defined as myocardial disorders in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, arterial hypertension, valvular disease, or congenital heart disease sufficient to cause the observed myocardial abnormality. Primarily, four distinct phenotypes are described: hypertrophic, dilated, restrictive, and arrhythmogenic. There are two additional unclassified cardiomyopathies (left ventricular noncompaction and Takotsubo cardiomyopathy). Each of these distinct phenotypes is comprised of genetic, familial, and nonfamilial forms.

During recent years there has been great progress made towards understanding the pathogenesis of myocardial diseases as well as in their diagnostics and treatment. Commercially available genetic testing, namely, next-generation sequencing techniques, has brought great diagnostic advancement in the assessment of inherited cardiomyopathies. A ‘big boom’ has been seen in multimodality imaging assessment of myocardial disorders. Furthermore, marked progress has been made within the arena of pharmacology and therapeutics (including both pharmacological and non-pharmacological strategies) that not only lowers morbidity but also can significantly improve mortality and the survival of affected individuals.

The aim of this special issue is to present a wide spectrum of original and review articles that focus on interesting and advancing areas within the topic of myocardial diseases.

Potential topics include, but are not limited to:

  • Hypertrophic cardiomyopathy: pathogenesis, nonsarcomeric phenocopies, diagnostic modalities, sudden death risk stratification, and pharmacological and nonpharmacological therapeutic options
  • Dilated cardiomyopathy: etiology, pathogenesis, diagnostic modalities, and therapeutic options (including CRT and ICD)
  • Myocarditis, inflammatory cardiomyopathy: diagnostic possibilities and therapeutic options
  • Arrhythmogenic cardiomyopathy: etiology, pathogenesis, diagnostic modalities, and therapeutic options, pharmacological and nonpharmacological
  • Restrictive cardiomyopathy: amyloid related disease and nonamyloid restrictive cardiomyopathies
  • Nonclassified cardiomyopathies: left ventricular noncompaction and Takotsubo cardiomyopathy
  • Myocardial involvement in neuromuscular disorders
  • Cardiotoxicity of cancer therapy

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 1720405
  • - Editorial

Myocardial Diseases: Current Views on Etiopathogenesis, Diagnostic Modalities, and Therapeutic Options

Tomas Palecek | Javier Ganame | Giovanni Di Salvo
  • Special Issue
  • - Volume 2016
  • - Article ID 4087632
  • - Review Article

Inflammatory Cardiomyopathy: A Current View on the Pathophysiology, Diagnosis, and Treatment

Jan Krejci | Dalibor Mlejnek | ... | Petr Nemec
  • Special Issue
  • - Volume 2016
  • - Article ID 1575130
  • - Review Article

Obstructive Form of Hypertrophic Cardiomyopathy-Left Ventricular Outflow Tract Gradient: Novel Methods of Provocation, Monitoring of Biomarkers, and Recent Advances in the Treatment

Pawel Petkow Dimitrow | Renata Rajtar-Salwa
  • Special Issue
  • - Volume 2016
  • - Article ID 1959270
  • - Research Article

Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance

Prema Robinson | Moses Kasembeli | ... | David J. Tweardy
  • Special Issue
  • - Volume 2016
  • - Article ID 9363951
  • - Research Article

Two-Dimensional Speckle Tracking Echocardiography Detects Subclinical Left Ventricular Systolic Dysfunction among Adult Survivors of Childhood, Adolescent, and Young Adult Cancer

Anthony F. Yu | Jayant Raikhelkar | ... | Jennifer E. Liu
  • Special Issue
  • - Volume 2016
  • - Article ID 8196560
  • - Review Article

The Causes of HIV-Associated Cardiomyopathy: A Tale of Two Worlds

Rebecca H. Lumsden | Gerald S. Bloomfield
  • Special Issue
  • - Volume 2016
  • - Article ID 2829583
  • - Review Article

Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis

Petr Kuchynka | Tomas Palecek | ... | Ales Linhart
  • Special Issue
  • - Volume 2015
  • - Article ID 762950
  • - Research Article

Vascular Endothelial Growth Factor Is Associated with the Morphologic and Functional Parameters in Patients with Hypertrophic Cardiomyopathy

Radek Pudil | Martina Vasatova | ... | Jiri Stulik
  • Special Issue
  • - Volume 2015
  • - Article ID 481245
  • - Research Article

Effect of Left Ventricular Outflow Tract Obstruction on Left Atrial Mechanics in Hypertrophic Cardiomyopathy

Lynne K. Williams | Raymond H. Chan | ... | Harry Rakowski
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